Rojas J, Castillo H, Mundaca M, Fraga J, Gilbert C, Valdebenito-Maturana B, Marcellini S. Liver-specific enhancers evolved from independent episodes of MITE domestication in Xenopus tropicalis. Mob DNA. 2025 Dec 4;16(1):46. doi: 10.1186/s13100-025-00384-7. PubMed PMID: 41345881; PubMed Central PMCID: PMC12676858.
Concha ML, Gaete M, Marcellini S, Palma V, Torrejón M, Vásquez-Doorman C. Developmental biology in Chile: an open window to Latin America and the world. Differentiation. 2025 Jul-Aug;144:100882. doi: 10.1016/j.diff.2025.100882. Epub 2025 Jun 16. PubMed PMID: 40570665.
Mundaca M, Rojas J, Cumilaf L, Jara F, Muñoz D, Pastenes L, Méndez M, Tovar LM, Torrejón M, Montoya-Sanhueza G, Marcellini S. Skull Ossification in the Andean Toad Rhinella spinulosa (Bufonidae) and the Genetic Model Organism Xenopus tropicalis (Pipidae) Reveals Heterochrony Phenomena and Frontoparietal Suture Modifications. J Exp Zool B Mol Dev Evol. 2024 Dec 4;. doi: 10.1002/jez.b.23280. [Epub ahead of print] PubMed PMID: 39629923.
Lanoizelet M, Michel L, Lagadec R, Mayeur H, Guichard L, Logeux V, Séverac D, Martin K, Klopp C, Marcellini S, Castillo H, Pollet N, Candal E, Debiais-Thibaud M, Boisvert C, Billoud B, Schubert M, Blader P, Mazan S. Analysis of a shark reveals ancient, Wnt-dependent, habenular asymmetries in vertebrates. Nat Commun. 2024 Nov 25;15(1):10194. doi: 10.1038/s41467-024-54042-2. PubMed PMID: 39587074; PubMed Central PMCID: PMC11589584.
Sandoval D, Mella J, Ojeda J, Bermedo-García F, Low M, Marcellini S, Castro MA, Casas M, Jaimovich E, Henríquez JP. The sodium/ascorbic acid co-transporter SVCT2 distributes in a striated membrane-enriched domain at the M-band level in slow-twitch skeletal muscle fibers. Biol Res. 2024 Nov 6;57(1):79. doi: 10.1186/s40659-024-00554-6. PubMed PMID: 39506870; PubMed Central PMCID: PMC11542426.
Castillo H, Hanna P, Sachs LM, Buisine N, Godoy F, Gilbert C, Aguilera F, Muñoz D, Boisvert C, Debiais-Thibaud M, Wan J, Spicuglia S, Marcellini S. Xenopus tropicalis osteoblast-specific open chromatin regions reveal promoters and enhancers involved in human skeletal phenotypes and shed light on early vertebrate evolution. Cells Dev. 2024 Sep;179:203924. doi: 10.1016/j.cdev.2024.203924. Epub 2024 Apr 29. PubMed PMID: 38692409.
Debiais-Thibaud M, Marin F, Marcellini S. Editorial: The evolution of biomineralization in metazoans. Front Genet. 2022;13:1092695. doi: 10.3389/fgene.2022.1092695. eCollection 2022. PubMed PMID: 36685829; PubMed Central PMCID: PMC9848429.
Martínez E, Marcellini S, Henríquez JP. Beyond vertebrates: the amphioxus as a relevant model system to explore the formation, organization, and regeneration of neuromuscular synapses. Neural Regen Res. 2022 Nov;17(11):2425-2426. doi: 10.4103/1673-5374.338994. PubMed PMID: 35535884; PubMed Central PMCID: PMC9120703.
Leurs N, Martinand-Mari C, Marcellini S, Debiais-Thibaud M. Parallel Evolution of Ameloblastic scpp Genes in Bony and Cartilaginous Vertebrates. Mol Biol Evol. 2022 May 3;39(5). doi: 10.1093/molbev/msac099. PubMed PMID: 35535508; PubMed Central PMCID: PMC9122587.
Muñoz-Montecinos C, Romero A, Sepúlveda V, Vira MÁ, Fehrmann-Cartes K, Marcellini S, Aguilera F, Caprile T, Fuentes R. Turning the Curve Into Straight: Phenogenetics of the Spine Morphology and Coordinate Maintenance in the Zebrafish. Front Cell Dev Biol. 2021;9:801652. doi: 10.3389/fcell.2021.801652. eCollection 2021. Review. PubMed PMID: 35155449; PubMed Central PMCID: PMC8826430.
Romero A, Leurs N, Muñoz D, Debiais-Thibaud M, Marcellini S. Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization. Front Genet. 2021;12:788346. doi: 10.3389/fgene.2021.788346. eCollection 2021. PubMed PMID: 34899866; PubMed Central PMCID: PMC8656109.
Debiais-Thibaud M, Simion P, Ventéo S, Muñoz D, Marcellini S, Mazan S, Haitina T. Skeletal Mineralization in Association with Type X Collagen Expression Is an Ancestral Feature for Jawed Vertebrates. Mol Biol Evol. 2019 Oct 1;36(10):2265-2276. doi: 10.1093/molbev/msz145. PubMed PMID: 31270539; PubMed Central PMCID: PMC6759074.
Aldea D, Subirana L, Keime C, Meister L, Maeso I, Marcellini S, Gomez-Skarmeta JL, Bertrand S, Escriva H. Genetic regulation of amphioxus somitogenesis informs the evolution of the vertebrate head mesoderm. Nat Ecol Evol. 2019 Aug;3(8):1233-1240. doi: 10.1038/s41559-019-0933-z. Epub 2019 Jul 1. PubMed PMID: 31263232.
Toro-Tapia G, Villaseca S, Beyer A, Roycroft A, Marcellini S, Mayor R, Torrejón M. The Ric-8A/Gα13/FAK signalling cascade controls focal adhesion formation during neural crest cell migration in Xenopus. Development. 2018 Nov 21;145(22). doi: 10.1242/dev.164269. PubMed PMID: 30297374; PubMed Central PMCID: PMC6262797.
Enault S, Muñoz D, Simion P, Ventéo S, Sire JY, Marcellini S, Debiais-Thibaud M. Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families. BMC Evol Biol. 2018 Aug 30;18(1):127. doi: 10.1186/s12862-018-1241-y. PubMed PMID: 30165817; PubMed Central PMCID: PMC6117938.
Muñoz D, Castillo H, Henríquez JP, Marcellini S. Bone regeneration after traumatic skull injury in Xenopus tropicalis. Mech Dev. 2018 Dec;154:153-161. doi: 10.1016/j.mod.2018.06.007. Epub 2018 Jul 2. PubMed PMID: 30420272.
Bermedo-García F, Ojeda J, Méndez-Olivos EE, Marcellini S, Larraín J, Henríquez JP. The neuromuscular junction of Xenopus tadpoles: Revisiting a classical model of early synaptogenesis and regeneration. Mech Dev. 2018 Dec;154:91-97. doi: 10.1016/j.mod.2018.05.008. Epub 2018 May 26. PubMed PMID: 29807117.
Otarola G, Castillo H, Marcellini S. Aryl hydrocarbon receptor-based bioassays for dioxin detection: Thinking outside the box. J Appl Toxicol. 2018 Apr;38(4):437-449. doi: 10.1002/jat.3575. Epub 2017 Dec 26. Review. PubMed PMID: 29277905.
Cervantes-Diaz F, Contreras P, Marcellini S. Evolutionary origin of endochondral ossification: the transdifferentiation hypothesis. Dev Genes Evol. 2017 Mar;227(2):121-127. doi: 10.1007/s00427-016-0567-y. Epub 2016 Dec 1. Review. PubMed PMID: 27909803.
Marcellini S, Escriva H. Editorial: Evolution of Organismal Form: From Regulatory Interactions to Developmental Processes and Biological Patterns. Front Genet. 2016;7:148. doi: 10.3389/fgene.2016.00148. eCollection 2016. PubMed PMID: 27582759; PubMed Central PMCID: PMC4987331.
Marcellini S, González F, Sarrazin AF, Pabón-Mora N, Benítez M, Piñeyro-Nelson A, Rezende GL, Maldonado E, Schneider PN, Grizante MB, Da Fonseca RN, Vergara-Silva F, Suaza-Gaviria V, Zumajo-Cardona C, Zattara EE, Casasa S, Suárez-Baron H, Brown FD. Evolutionary Developmental Biology (Evo-Devo) Research in Latin America. J Exp Zool B Mol Dev Evol. 2017 Jan;328(1-2):5-40. doi: 10.1002/jez.b.22687. Epub 2016 Aug 5. Review. PubMed PMID: 27491339.
Fritz A, Bertin A, Hanna P, Nualart F, Marcellini S. A Single Chance to Contact Multiple Targets: Distinct Osteocyte Morphotypes Shed Light on the Cellular Mechanism Ensuring the Robust Formation of Osteocytic Networks. J Exp Zool B Mol Dev Evol. 2016 Jul;326(5):280-9. doi: 10.1002/jez.b.22683. Epub 2016 Jul 6. PubMed PMID: 27381191.
Enault S, Muñoz DN, Silva WT, Borday-Birraux V, Bonade M, Oulion S, Ventéo S, Marcellini S, Debiais-Thibaud M. Molecular footprinting of skeletal tissues in the catshark Scyliorhinus canicula and the clawed frog Xenopus tropicalis identifies conserved and derived features of vertebrate calcification. Front Genet. 2015;6:283. doi: 10.3389/fgene.2015.00283. eCollection 2015. PubMed PMID: 26442101; PubMed Central PMCID: PMC4584932.
Bertin A, Hanna P, Otarola G, Fritz A, Henriquez JP, Marcellini S. Cellular and molecular characterization of a novel primary osteoblast culture from the vertebrate model organism Xenopus tropicalis. Histochem Cell Biol. 2015 Apr;143(4):431-42. doi: 10.1007/s00418-014-1289-8. Epub 2014 Nov 5. PubMed PMID: 25371327.
Vera A, Stanic K, Montecinos H, Torrejón M, Marcellini S, Caprile T. SCO-spondin from embryonic cerebrospinal fluid is required for neurogenesis during early brain development. Front Cell Neurosci. 2013;7:80. doi: 10.3389/fncel.2013.00080. eCollection 2013. PubMed PMID: 23761733; PubMed Central PMCID: PMC3669746.
Aldea D, Hanna P, Munoz D, Espinoza J, Torrejon M, Sachs L, Buisine N, Oulion S, Escriva H, Marcellini S. Evolution of the vertebrate bone matrix: an expression analysis of the network forming collagen paralogues in amphibian osteoblasts. J Exp Zool B Mol Dev Evol. 2013 Sep;320(6):375-84. doi: 10.1002/jez.b.22511. Epub 2013 May 15. PubMed PMID: 23677533.
Fuentealba J, Toro-Tapia G, Arriagada C, Riquelme L, Beyer A, Henriquez JP, Caprile T, Mayor R, Marcellini S, Hinrichs MV, Olate J, Torrejón M. Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration. Dev Biol. 2013 Jun 15;378(2):74-82. doi: 10.1016/j.ydbio.2013.04.005. Epub 2013 Apr 12. PubMed PMID: 23588098.
Bertrand S, Fuentealba J, Aze A, Hudson C, Yasuo H, Torrejon M, Escriva H, Marcellini S. A dynamic history of gene duplications and losses characterizes the evolution of the SPARC family in eumetazoans. Proc Biol Sci. 2013 Apr 22;280(1757):20122963. doi: 10.1098/rspb.2012.2963. Print 2013 Apr 22. PubMed PMID: 23446527; PubMed Central PMCID: PMC3619480.
Sandoval D, Ojeda J, Low M, Nualart F, Marcellini S, Osses N, Henríquez JP. The vitamin C transporter SVCT2 is down-regulated during postnatal development of slow skeletal muscles. Histochem Cell Biol. 2013 Jun;139(6):887-94. doi: 10.1007/s00418-012-1075-4. Epub 2013 Jan 18. PubMed PMID: 23329419.
Marcellini S, Henriquez JP, Bertin A. Control of osteogenesis by the canonical Wnt and BMP pathways in vivo: cooperation and antagonism between the canonical Wnt and BMP pathways as cells differentiate from osteochondroprogenitors to osteoblasts and osteocytes. Bioessays. 2012 Nov;34(11):953-62. doi: 10.1002/bies.201200061. Epub 2012 Aug 29. Review. PubMed PMID: 22930599.
Espinoza J, Sanchez M, Sanchez A, Hanna P, Torrejon M, Buisine N, Sachs L, Marcellini S. Two families of Xenopus tropicalis skeletal genes display well-conserved expression patterns with mammals in spite of their highly divergent regulatory regions. Evol Dev. 2010 Nov-Dec;12(6):541-51. doi: 10.1111/j.1525-142X.2010.00440.x. PubMed PMID: 21040421.
Marcellini S, Bruna C, Henríquez JP, Albistur M, Reyes AE, Barriga EH, Henríquez B, Montecino M. Evolution of the interaction between Runx2 and VDR, two transcription factors involved in osteoblastogenesis. BMC Evol Biol. 2010 Mar 17;10:78. doi: 10.1186/1471-2148-10-78. PubMed PMID: 20236534; PubMed Central PMCID: PMC2848158.
Bielen H, Oberleitner S, Marcellini S, Gee L, Lemaire P, Bode HR, Rupp R, Technau U. Divergent functions of two ancient Hydra Brachyury paralogues suggest specific roles for their C-terminal domains in tissue fate induction. Development. 2007 Dec;134(23):4187-97. doi: 10.1242/dev.010173. PubMed PMID: 17993466.
Marcellini S, Technau U, Smith JC, Lemaire P. Evolution of Brachyury proteins: identification of a novel regulatory domain conserved within Bilateria. Dev Biol. 2003 Aug 15;260(2):352-61. doi: 10.1016/s0012-1606(03)00244-6. PubMed PMID: 12921737.