Sylvain Marcellini
Principal Investigator
Xenbase web page
ResearcherID
ORCID
smarcellini@udec.cl
Office: (56)41-2 203 295
Lab: (56)41-2 204 135
Hector Castillo
PhD student
hecastillo@udec.cl
(56)41-2 201 660
Hector is developing new expression vectors and experimental strategies to detect toxic compounds such as dioxins.
Marco mundaca
PhD student
marmundaca@udec.cl
(56)41-2 201 660
Marco´s project is focussed on regulatory and metabolic rewiring of osteoblasts between Xenopus laevis and Xenopus tropicalis.
Japhet Rojas
PhD student
japhetrojas@udec.cl
(56)41-2 201 660
Japhet is studying how transposable elements have been domesticates into ubiquitous or tissue-specific enhancers in the Xenopus genus.
Lefney Cumilaf
Biology Undergraduate student
lcumilaf2020@udec.cl
(56)41-2 201 660
Lefney is examining how the expression strength of genes related to the production of a collagenous bone matrix has evolved between Xenopus laevis and Xenopus tropicalis.
Guillermo Ditzel
Bioengineering Undergraduate student
gditzel2019@udec.cl
(56)41-2 201 660
Guillermo is studying the temporal activation of stemness genes during skull regeneration.
Francisco Godoy
Bioinformatician
(56)41-2 201 660
Bioinformatic analyses of our RNA-seq and ChIP-seq experiments performed on developing Xenopus tropicalis skeletal cells.
Former members
Isidora Sovino. Isidora defended her Bioengineering undergraduate thesis in October 2023. She studied the spatial relationship of osteogenesis and angiogenesis during skull bone regeneration.
Jorge Fraga. Jorge defended his Biochemistry undergraduate thesis in September 2022. He studied transposable elements enriched at active enhancers in Xenopus tropcialis.
Adrián Romero. Adrian defended his PhD thesis in November 2021. He studied the regulatory architecture of the SCPP locus by performing 4C on Xenopus tropicalis primary oetsoblasts.
David Muñoz. David defended his PhD thesis in 2020. He explored the possible homology of bone and dentine from a GRN perspective.
Fret Cervantes. Fret defended his PhD thesis in 2020. He examined the evolution of the skeletal expression of Sox9.
Pedro Contreras. Pedro defended his Master thesis in May 2017, focused on the functional impact of repeated sequences embedded within a col1a1 distal enhancer.
Gastón Ótarola. Gaston performed both his bioingineering undergraduate thesis and his master thesis in the LADE between 2011 and 2014, and developed a new dioxin bioassay. Albeit he is now performing a PhD thesis in Berkeley, we still collaboratee on this topic.
Patricia Hanna. Patricia performed her PhD in the LADE between 2010 and 2014. She successfully used RNA-seq and ChIP-seq to detect active/poised promoters and enhancers in Xenopus tropicalis osteoblasts, and study the complex relationship between regulatory elements and repeated sequences.
Ariana Bretin. Ariana performed her PhD in the LADE between 2010 and 2014, she established a primary culture of Xenopus osteoblasts and studied the activity of the Wnt and BM pathways in vivo and in vitro.
Alan ritz. Alan did his undergraduate Biochemistry thesis in the LADE between 2013 and 2014. He performed a detailed 3D imaging of native Xenopus tropicalis osteocytes which provided important insights regarding how osteocytogenesis occurs in vivo.
David Navarro. David did his undergraduate Biology thesis in the LADE between 2013 and 2014, focusing on the evolution of the btg family members.
Daniel Aldea. Daniel did his undergraduate Biochemistry thesis in the LADE between 2011 and 2012, focusing on the evolution of the network-forming collagen family.
Federico Jara. Federico did his undergraduate Biology research project (“Licenciatura”) in the LADE in 2011. His work focused on the anatomical comparison of skeletal development between Xenopus tropicalis and Chilean endemic frog species.
Javier Espinoza. Javier did his undergraduate Biology thesis in the LADE between 2008 and 2010. His work focused on the histological analysis of bone development in Xenopus tropicalis, as well as on the description of gene expression patterns.
Mario Sanchez. Mario did his undergraduate Biochemistry thesis in the LADE between 2008 and 2009. His work focused on the molecular characterization of Xenopus tropicalis skeletal genes, as well as on the cloning of new transgenesis vectors.